Why Shouldn't You Take Medicine with Grapefruit Juice?
Why Shouldn't You Take Medicine with Grapefruit Juice?
If you’ve taken prescription medication, have you ever noticed the strange disclaimer, “don’t take with grapefruit juice”? There is a very good reason for that! Hank Green explains in this episode of SciShow Quick Questions!
Hosted by: Hank Green
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Sources:
http://www.dictiome.com/en/27682/furanocoumarins-pronunciation-Aussprache-prononciation-%D0%BF%D1%80%D0%BE%D0%B8%D0%B7%D0%BD%D0%BE%D1%88%D0%B5%D0%BD%D0%B8%D0%B5-pronunciaci%C3%B3n [pronunciation]
http://ajcn.nutrition.org/content/83/5/1097.long
http://www.fda.gov/downloads/ForConsumers/ConsumerUpdates/UCM292839.pdf
http://www.health.harvard.edu/family_health_guide/grapefruit-and-medication-a-cautionary-note
http://www.cancer.net/navigating-cancer-care/how-cancer-treated/clinical-trials/phases-clinical-trials
I just took a perc with a glass of grapefruit juice, see you on the other side.
What about grapefruit cordial , diluted with water?
Grapefruits are my favorite fruits
This is a serious thing. Take ketamine, for example. Studies have shown that patients who ingested grapefruit prior to a slow-drip IV infusion of race mix ketamine had 3-fold the blood plasma levels of S-ketamine alone in the area under the curve (translation: it was 3X as powerful in grapefruit+ people). No, this doesn’t mean take some grapefruit and you can cut your doses fractionally (in ketamine’s case, by appx. one-third), as the mechanisms of CYP enzymes are complex and you could, in fact, be diminishing the effects of your drug, such would be the case for a pro-drug that needs the enzyme for conversion (like Tramadol). It can be extremely dangerous. I wish more people knew about this, it would literally save lives.
I can’t eat grapefruit because of my meds … I honestly miss it
Maybe the grapefruit will take care of the problem the medication is being used for.
I’m taking some antibiotics right now for a stye and the pharmacist told me this exact warning. Well, I don’t even like grapefruit anyways so I’m not missing out on anything great. (grapefruit is too bitter for my tastes)
Appreciate video content! Apologies for chiming in, I would appreciate your initial thoughts. Have you ever tried – Dinanlinson Collecting Muscle Approach (do a google search)? It is a smashing one of a kind guide for learning how to get big and lean fast without the normal expense. Ive heard some awesome things about it and my GF at very last got excellent success with it.
Thank you I’ve always hated grapefruit but I’m about to get lit tonight
The way you talk is very nice to listen to sir
I like grapefruit juice.
luls
Thank you for the best explanation.
I prefer pomelo.
Hank you have obviously never had the "Simply" brand pink grapefruit juice because that right there is what we call Heavenly Dank! Once you’ve had Simply Grapefruit, that there piddily orange juice can be tea-bagged! Because "Meh!" just doesn’t cut it anymore!
I’ll never drink grapefruit juice ever again
Well I’ll guess I’ll die just took it with headache meds
Moriarty the patriot brought me here.
I drank a whole big bottle of white grape fruit juice once for that exact reason
Don’t take grapefruit juice with your medication.
If you take your medication in the morning, you could have your grapefruit in the afternoon.
Who’s here for kratom and grapefruit juice?
I always drink a carton of grapefruit juice with my valium!
I kno this and I still take my meds with grapefruit juice because we only have one life and I’ll be darned if big pharma denies me every mg of my dose LISTEN TO HANK THO
Pink grapefruit juice the best
If you take sprycal for CML don’t drink grapefruit juice either.
Definitely going to the store to buy grapefruit juice…
Cough medicine like dextromethorphan helps dry cough but if you take more than the recommended dose it becomes a dissociative drug and if you take enough of it you can have an out of body experience while tripping. You can mix grapefruit juice with this and it infact gives more visuals, the visuals look like LSD visuals.
But can we use this method to reduce the required dose and bring down drug costs?
Just ate grapefruit and took my meds o my hope I live . God bless .
Now I will take my aspirin as well as grapefruit juice to get rid of a headache faster
Grapefruit increases opiates and makes them last longer except certain synthetic versions like tramadol actually keeps it from working. It depends on how the drug works, is it active before or after metabolism by the enzyme it inhibits? Sometimes I forget and mix with caffeine stayed up all night unfortunately.
Most deceptive "fruit" in the world
No it does not…orange juice is too sweet! But that list is worrisome, as those are all drugs I take…
They work out a safe dose ? Ok I’m drinking grapefruit with my drugs who wants to stay safe?
This is a weird question, but why does adderall make me fall asleep? I mean I’m not complaining because I usually go 1-5 days without sleep but I thought it was supposed to make me focus. Any help is appreciated.
Fake theories.Scientist proved this theory wrong…(they experimented with this interaction on people,the effect is a placebo effect)…I do not know how people belive eveything on the internet.
Will grapefruit juice increase the dose of Viagra?
Grape fruit is the only fruit I do not like
I’ve been drinking a lot of GF Juice lately and I also take a lot of different medications. Man have I been feeling it. My heart has been beating really fast, I’ve been jittery, sweaty palms and feeling pretty crappy. I’m off of it now and feel a lot better.
I see this guy more than I see my mom
I just drank a whole bottle of grapefruit cider without realising. . .
You telling me I’ll get higher if I take drugs with a shot of grapefruit juice?
Lovely Video clip! Sorry for the intrusion, I would appreciate your initial thoughts. Have you tried – Dinanlinson Collecting Muscle Approach (do a search on google)? It is a smashing one off product for learning how to get big and lean fast without the headache. Ive heard some pretty good things about it and my friend got astronomical success with it.
Couldn’t you just cut your dose in half and take with grapefruit? It would effectively double the amount of doses you have for the same cost… ofcourse pharm companies would hate that.
So what if you take half the amount of medication recommended with a glass of grapefruit juice?!? Would this be just right?
Nope. I like me my grapefruit juice. I also take atorvastatin. The best way to manage interactions like this (according to my doctor) is to space them out by at least two hours. I eat grapefruit in the morning and take my meds at bedtime.
10mg codeine + 1 litre grapefruit juice, I’m feeling something
Can’t you use the grapefruit juice to save money since you can just purchase medicine with a lower dose
I ate one grapefruit a day wow